Olefin metathesis in air
- Lorenzo Piola,
- Fady Nahra and
- Steven P. Nolan
Beilstein J. Org. Chem. 2015, 11, 2038–2056, doi:10.3762/bjoc.11.221
Graphical Abstract
Scheme 1: Polymerization of 7-oxanorbornene in water.
Scheme 2: Synthesis of the first well-defined ruthenium carbene.
Scheme 3: Synthesis of Grubbs' 1st generation catalyst.
Figure 1: NHC-Ruthenium complexes and widely used NHC carbenes.
Scheme 4: Access to 21 from the Grubbs’ 1st generation catalyst and its one-pot synthesis.
Scheme 5: Synthesis of supported Hoveyda-type catalyst.
Figure 2: Scope of RCM reactions with supported Hoveyda-type catalyst. Reaction conditions: 24 (5 mol %), non...
Scheme 6: Synthesis of 33 by Hoveyda and Blechert.
Figure 3: Synthesis of chiral Hoveyda–Grubbs type catalyst and its use in RO/CM.
Scheme 7: Synthesis of 41.
Figure 4: RCM reactions in air using 41 as catalyst. Reaction conditions: 41 (5 mol %), MeOH (0.05 M), 22 °C,...
Figure 5: CM-type reactions in air using 41 as catalyst. Reaction conditions: 41 (5 mol %), 22 °C, 12 h, in a...
Figure 6: Grela's complex (54) and reaction scope in air. Reaction conditions: catalyst, substrate (0.25 mmol...
Figure 7: Abell's complex (61) and its RCM reaction scope in air. Reaction condition: 10 mol % of 61, refluxi...
Figure 8: Catalysts used by Meier in air.
Figure 9: Ammonium chloride-tagged complexes.
Figure 10: Scorpio-type complexes.
Scheme 8: Synthesis of Grubbs' 3rd generation catalyst.
Figure 11: Indenylidene complexes.
Figure 12: Commercially available complexes evaluated under air.
Figure 13: Grela's N,N-unsymmetrically substituted complexes.
Scheme 9: Synthesis of phosphite-based catalysts.
Figure 14: Catalysts used by the Cazin group.
Figure 15: RCM scope in air with catalysts 33, 85 and 98a. Reaction conditions: Catalyst, substrate (0.25 mmol...
Figure 16: Synthesis of Schiff base-ruthenium complexes.
Scheme 10: Schiff base–ruthenium complexes synthesized by Verpoort.
Scheme 11: Synthesis of mixed Schiff base–NHC complexes.
Figure 17: Veerport's indenylidene Schiff-base complexes.
